I had an Ocrevus infusion last Friday and I love the new faster infusion method! We were talking about when I would have allergic reactions before I switched to Claritin instead of Benadryl and the guy two seats over said he was itchy and turned out he was having an allergic reaction. I apologized for "bringing it on" by talking about it. He got more Benadryl and was fine. Benadryl works fine but the problem is it wears off faster than Claritin.